Naltrexone is used as an off-label treatment in low doses for several chronic immune-modulated disorders in many countries. Although only small-scale clinical trials have been performed, these suggest ...

A man in his late 40s with no known past medical history was unresponsive for an unknown period of time. Crushed pills and white residue were found on a nearby table. On presentation he was obtunded ...

Immunoglobulin A nephropathy (IgAN) is the most commonly diagnosed glomerulonephritis worldwide. It is usually idiopathic and may be associated with many other diseases. Recently, biological agents ...

Guillain-Barré Syndrome (GBS) and cervical myelopathy are rare coexisting conditions in paediatric patients, often leading to significant diagnostic challenges due to their overlapping symptoms. We ...

This case series documents three patients referred to the Intensive Dietary Management clinic in Toronto, Canada, for insulin-dependent type 2 diabetes. It demonstrates the effectiveness of ...

Drug abuse by inhalation of volatile household product substances is uncommon, however, it can have devastating consequences. This case report describes the fatal outcome of deodorant inhalation by a ...

Despite the perception that medical students and doctors should be ‘invincible’, mental health challenges are common in this population. Medical students and doctors have low levels of help seeking ...

A 50-year-old man with a polycystic kidney disease, awoke from sleep with unilateral jaw swelling. As demonstrated in the accompanying [figure 1][1], the oedema progressed over a period of 6 hours to ...

Adrenal incidentalomas, mostly adrenal adenomas, affect 3%–10% of the global population. Adrenocortical carcinoma (ACC) is rare, with an incidence of 0.7–2 cases per million. Adrenocortical oncocytic ...

Erythema nodosum (EN) is a common dermatological manifestation with many different aetiologies. Often however, the aetiology remains unidentified. We present here a 42-year-old male patient with an EN ...

A 61-year-old man presented to the ENT emergency clinic with a history of unilateral facial nerve palsy occurring shortly after each dose of the Pfizer-BioNTech COVID-19 vaccine. The first episode ...

Vogt-Koynagi-Harada (VKH) disease is a clinical syndrome with classical ocular and extraocular findings that is not uncommonly described in Asian, Middle-Eastern and South American populations. We ...