MASLD has become the most common chronic liver disease worldwide. The authors review the features of the disease as well as ...

A 56-year-old woman experiencing homelessness was evaluated at this hospital because of sore throat and a pruritic rash on her face, chest, abdomen, and legs. A diagnosis was made. What is the ...

To prevent the spread of inaccurate information, academic and health care institutions will need to equip scientists and clinicians to engage effectively on nontraditional media platforms.

This Double Take video explores the link between certain strains of human papillomavirus and cancer and reviews the evidence ...

Explore Interactive Medical Case articles from The New England Journal of Medicine ...

NEJM uses highly rigorous editorial, peer, and statistical review processes to evaluate manuscripts for scientific accuracy, novelty, and importance.

In 15 patients with primary aldosteronism, baxdrostat (a second-generation, nonimidazole aldosterone synthase inhibitor) resolved or reduced the severity of hypertension, excessive aldosterone ...

The Trump administration’s proposed 15% cap on indirect-cost rates for National Institutes of Health grants risks upending the paradigm that underpins American leadership in medical research.

A woman with aggressive refractory systemic lupus erythematosus was treated with a short course of the bispecific antibody teclistamab (anti–B-cell maturation antigen and anti-CD3) and had a ...

The FDA often exercises flexibility in deciding whether to approve highly promising drugs for patients in desperate need of treatment options. But it doesn’t consider a drug’s likely financial ...

The exclusively human pathogen Neisseria meningitidis, which was first described in 1805 after an outbreak of 33 cases in Geneva, Switzerland, has been feared worldwide for more than 215 years as a ...

During 2018–2024, the percentage of N. gonorrhoeae isolates carrying tetM, which confers tetracycline resistance, increased from less than 10% to more than 30% across the United States.