Dynein is a molecular motor involved in many cellular functions. The motor domain of dynein contains six AAA+ domains forming a ring that interacts with the motile linker domain. The structure of ...

The problem of minimizing a concave function subject to linear inequality constraints may have many local solutions. Therefore, finding the global constrained minimum is a computationally difficult ...

Because DIX domain obviously inhibits the transcriptional activity of LEF-1 induced by Wnt-3a CM and overexpressed Dvl-1, its function should be defined at the downstream of Dvl.