Conclusion Prostate cancer is surprisingly prevalent in men with serum PSA levels that are considered by many clinicians to be in the normal range (i.e. ≤4.0 ng/ml).

Lowering the biopsy indication to a PSA level of 2.5 ng/ml would increase the number of prostate cancers diagnosed in the US to more than 775,000 per year, resulting in a ratio of 25:1 for men ...

These findings are unique in that typically men are not recommended for a prostate biopsy until their PSA levels rise above 4 ng/mL. Larger studies with longer follow-up are needed to confirm ...

Background: Prostate Specific Antigen (PSA) is one of the most important tumor markers in oncology. However, its use is controversial for early detection of prostate cancer due in part to ...

However, a PSA level between 4 and 10 ng/mL is considered suspicious and may require a repeat test. PSA is secreted in large amounts by prostate cancer cells.

For men with a PSA level more than 4 ng/mL, a PSA velocity of 0.75 ng/mL/yr or less has been suggested to identify men with slow-growing cancers or benign prostatic disease and who therefore may not ...

prostate cancer occurred in only 15.2% of men with a PSA level at or below 4.0 ng/ml – Hence came about the suggestions of having different levels for different age groups ...

Doctors who use age-adjusted levels usually suggest that men younger than age 50 should have a PSA level below 2.4 ng/mL, while a PSA level up to 6.5 ng/mL would be considered normal for men in ...

The characteristics of the patients are shown in Table 1. The median age and PSA at diagnosis were 73 years (range 50 to 92) and 174 ng/mL (range 5.7 to 21864), respectively. The median follow-up ...

After adjustment for absolute PSA level, Gleason score, and tumor category, having PSA velocity >2 ng/mL was associated significantly with a 12-fold increased risk for prostate-cancer death and a ...

“Clinical trials of prostate cancer screening used PSA levels of 2.5 to 4.0 ng/mL as a threshold for biopsy, although in practice, both Black and white men were referred at higher PSA levels ...

And so this causes many men that have elevated PSA levels to be falsely elevated -- that is not caused by prostate cancer. In fact, it's wrong 80 percent of the time.